This website was created as a project for Genetics 677, an undergraduate course at UW Madison.
WRN Gene
Figure illustrates location of WRN gene within chromosome 8
WRN is the gene linked to Werner syndrome. It is a member of the RecQ family of helicases, meaning it is a DNA helicase homologue. WRN is located on the short arm of chromosome 8. There are 7 homologues that share sequence similarity with the human form of the protein, WRN. Using the slide out menu while holding the cursor over "gene analysis" will navigate to WRN gene sub-menus including: homology, ontology, DNA motifs, RNAi, and DNA microarrays.
Gene Location: locus 8p12-p11.2
DNA length: 140,499 base pairs, Accession number NC_000008.10
mRNA length: 5,765 base pairs, Accession number NM_000553.4
DNA length: 140,499 base pairs, Accession number NC_000008.10
mRNA length: 5,765 base pairs, Accession number NM_000553.4
References
1. National Center for Biotechnology Information. Werner syndrome ATP-dependent helicase [homo sapiens]. Gene summary. Bethesda (MD): HUGO gene nomenclature committee; March 2010.
2. National Center for Biotechnology Information. Werner syndrome ATP-dependent helicase [homo sapiens]. Gene FASTA. Bethesda (MD): HUGO gene nomenclature committee; March 2010.
3. National Center for Biotechnology Information. Werner syndrome ATP-dependent helicase [homo sapiens]. mRNA FASTA. Bethesda (MD): HUGO gene nomenclature committee; March 2010.
4. (Title figure) WRN gene locus. Retrieved March 13, 2010.
2. National Center for Biotechnology Information. Werner syndrome ATP-dependent helicase [homo sapiens]. Gene FASTA. Bethesda (MD): HUGO gene nomenclature committee; March 2010.
3. National Center for Biotechnology Information. Werner syndrome ATP-dependent helicase [homo sapiens]. mRNA FASTA. Bethesda (MD): HUGO gene nomenclature committee; March 2010.
4. (Title figure) WRN gene locus. Retrieved March 13, 2010.
